E-100 would not work, E-75 and E-50 were just upgraded Tiger II and Panther with some sort of compatibility but the best of E-series was actually E-25. When you look at postwar Kanonen jagdpanzer and Raketen jagdpanzer, they are very similar to E-25. If Germans focused on medium tanks and TD's instead of heavy tanks (Panther with 45 tonnes is more heavy than medium tank), they would last longer.
DEAR GOD NO, I HATE STRUMPANZER MAUS!
to be honest the E100 was supposed to be maus 2 but it wasnt created...and the germans were desperate but...adding a sturmtiger gun to a maus slightely works out... its a heavy Sturmtiger with a turret.
yes adding a "E100" turret on a maus and call it Maus 2.... or hey adding a Anti-aircraft turret to a Super heavy tank with a thin roof....
or landcruiser , if on english
@Bigboomstuff , it is landkreuzer