Yah.. April feewl?
Changing the mouse settings to left handed (or right handed) is fun. They usually don't know what is going on!
I know open cmd (windows) the type
shutdown -s -f -t 12000
the type
exit
or
maybe enable this
http://support.microsoft.com/kb/244139
then make a batch file that makes then press right ctrl + scroll lock + scroll lock